F083 Chronic Urticaria: What's New
DESCRIPTION
The purpose of this session is to highlight the recent major advances in this field as CSU and CIndU cases continue to persist despite being treated with antihistamines, oral corticosteroids and Omalizumab. Furthermore dermatologists will be presented with diagnostic and treatment algorithms based on evidence-based guidelines, and patient specific factors. In addition the dermatologists will be presented with emerging biologic therapies that will be launched soon and new drugs in the pipeline that target CSU and CIndU.
LEARNING OBJECTIVES
Recognize Spontaneous CU (CSU) and Inducible CU (CIndU) through identification of the clinical symptoms and associated biomarker testing
Describe evidence-based strategies for treatment selection considering clinical guidelines and patient-specific factors
Review and describe the mechanisms of CSU and emerging biologic therapies and small molecules in the treatment of CSU and CIndU
DIRECTOR
Gil Yosipovitch, MD
CO-DIRECTOR
Martin Metz, MD
SPEAKERS
Ana M Gimenez-Arnau, MD, IFAAD
Brian S Kim, MD, FAAD
Elena Netchiporouk
DISCLOSURES
Ana M Gimenez-Arnau, MD, IFAAD
Almirall – Advisory Board(Fees); Amgen – Advisory Board(Fees); AstraZeneca – Investigator(Grants/Research Funding); Avene – Speaker(Fees); Blueprint Medicines – Advisory Board(Fees); Celldex – Investigator(Grants/Research Funding); celtrium – Advisory Board(Honoraria); Escient – Investigator(Grants/Research Funding); Evommune – Advisory Board(Honoraria); Genentech – Investigator(Grants/Research Funding); Grupo Menarini Centroamerica – Speaker(Fees); GSK – Advisory Board(Fees); Harmonic Bio – Advisory Board(No Compensation Received); Incyte Corporation – Advisory Board(No Compensation Received); Instituto de Salud Carlos III – Investigator(Grants/Research Funding); Jasper Therapeutics – Advisory Board(Fees); Leo Pharma – Investigator(Grants/Research Funding); Mitsubishi Tanabe Pharma Development America – Advisory Board(Fees); Noucor, – Advisory Board(Fees); Novartis Pharmaceuticals Corp. – Advisory Board(Fees), Investigator(Grants/Research Funding); Pfizer – Advisory Board(No Compensation Received); RAPT Therapeutics – Advisory Board(Honoraria); Sanofi–Regeneron – Advisory Board(Fees), Investigator(Grants/Research Funding); Septerna – Advisory Board(Fees); Servier – Advisory Board(Fees);
Brian S Kim, MD, FAAD
AbbVie – Consultant(Fees); Almirall – Advisory Board(Honoraria); Alys Pharmaceuticals – Stockholder Private Company(Stock); AstraZeneca – Consultant (1099 relationship)(Fees); Eli Lilly and Company – Advisory Board(Honoraria); Evommune, Inc. – Consultant (1099 relationship)(Fees); Galderma – Consultant (1099 relationship)(Fees); Guidepoint Global, LLC – Consultant(Fees); Leo Pharma Inc. – Consultant(Fees), Investigator(Grants/Research Funding); Locus Biosciences – Stockholder(Stock); Novartis – Advisory Board(Honoraria); Pfizer Inc. – Consultant(Honoraria); Recens Medical – Consultant(Fees); Regeneron – Consultant (1099 relationship)(Honoraria); Sanofi – Consultant(Fees); Septerna – Consultant (1099 relationship)(Fees);
Martin Metz, MD
AbbVie – Speaker(Honoraria); Allakos – Investigator(No Compensation Received); Allegria Therapeutics – Advisory Board(Honoraria); Almirall – Speaker(Honoraria), Speaker/Faculty Education(Honoraria); Amgen – Advisory Board(Honoraria); Arcutis Biotherapeutics – Advisory Board(Honoraria); argenx – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria); AstraZeneca – Advisory Board(Honoraria); Astria Therapeutics – Advisory Board(Honoraria); Attovia Therapeutics – Consultant (1099 relationship)(Honoraria); Bayer – Consultant (1099 relationship)(Honoraria); Berlin Chemie – Speaker(Honoraria); Blueprint Medicines – Advisory Board(Honoraria); candid – Consultant (1099 relationship)(Honoraria); Celldex – Advisory Board(Honoraria); Celltrion – Speaker(Honoraria); Deep Apple Therapeutics – Advisory Board(Honoraria); Eli Lilly – Advisory Board(Honoraria); Enanta Pharmaceuticals – Consultant (1099 relationship)(Honoraria); Escient Pharmaceuticals, Inc – Advisory Board(Honoraria); Evommune, Inc. – Advisory Board(Honoraria); Excellergy – Consultant (1099 relationship)(Honoraria); FatiAbGen – Consultant (1099 relationship)(Honoraria); Galderma – Advisory Board(Honoraria), Speaker(Honoraria); Generate Biomedicines – Consultant (1099 relationship)(Honoraria); GlaxoSmithKline Immunology – Advisory Board(Honoraria); Granular Therapeutics – Advisory Board(Honoraria); Incyte Corporation – Advisory Board(Honoraria); InflaRx – Consultant (1099 relationship)(Honoraria); Japan Tobacco Inc. – Consultant (1099 relationship)(Honoraria); Jasper Therapeutics – Advisory Board(Honoraria); Johnson & Johnson Pharmaceutical Research & Development – Advisory Board(Honoraria); Lycia Therapeutics – Consultant (1099 relationship)(Honoraria); Novartis – Advisory Board(Honoraria), Speaker(Honoraria); Ono – Consultant (1099 relationship)(Honoraria); Pfizer Inc. – Speaker(Honoraria); RAPT Therapeutics – Advisory Board(Honoraria); Regeneron Pharmaceuticals, Inc. – Advisory Board(Honoraria); Sanofi – Advisory Board(Honoraria), Speaker(Honoraria); Santa Ana Bio – Advisory Board(Honoraria); Septerna – Advisory Board(Honoraria); Tupos – Consultant (1099 relationship)(Honoraria);
Elena Netchiporouk
AbbVie – Consultant (1099 relationship)(Honoraria), Speaker(Honoraria); Arcutis, Inc. – Consultant (1099 relationship)(Honoraria); Bausch Health – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Speaker(Honoraria); Biojamp – Consultant (1099 relationship)(Honoraria); Boehringer Ingelheim International – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Bristol Myers Squibb – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Speaker(Honoraria); Celltrion – Consultant (1099 relationship)(Honoraria), Speaker(Honoraria); Eli Lilly – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Galderma – Consultant (1099 relationship)(Honoraria), Speaker(Honoraria); Innovaderm Research Inc. – Investigator(Grants/Research Funding); janssen – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Speaker(Honoraria); Leo Pharma – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Medexus – Consultant (1099 relationship)(Honoraria); Novartis Pharmaceuticals Corporation – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Pfizer Inc. – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Speaker(Honoraria); Sanofi Genzyme – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Searchlight Pharma – Consultant (1099 relationship)(Honoraria); Sun Pharmaceutical Industries Ltd. – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria); UCB – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Speaker(Honoraria);
Gil Yosipovitch, MD
AbbVie – Advisory Board(Honoraria); Arcutis, Inc. – Advisory Board(Honoraria); Cara Therapeutics – Advisory Board(Honoraria); CeraVe – Advisory Board(Honoraria); Eli Lilly – Investigator(Fees), Investigator(Grants/Research Funding); Eli Lilly and Company – Advisory Board(Honoraria); escient – Investigator(Fees), Investigator(Grants/Research Funding); Galderma – Advisory Board(Honoraria); Galderma Laboratories, L.P. – Consultant(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); GSK – Advisory Board(Honoraria); Kamari Pharma – Consultant(Fees); Kiniksa Pharmaceuticals, Ltd. – Investigator(Grants/Research Funding); Maruho Co., Ltd – Speaker/Faculty Education(Fees); Novartis – Consultant(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); Pfizer Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Pierre Fabre – Consultant(Honoraria); Sanofi/Regeneron – Advisory Board(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); Vifor Pharma – Consultant(Fees);