S002 Chronic Pruritus: Bedside to Bench Perspectives
DESCRIPTION
Itch impacts quality of life to the same extent as chronic pain. Advances in understanding itch has resulted in a revolution in therapies. This session is geared toward the practicing physician. It addresses itch from children with atopic dermatitis, to the elder population, and those who itch from the adverse impact of immunomodulators used to treat melanoma. This activity has been approved by the American Board of Dermatology (ABD) for up to 30 Continuing Certification Program (CCP) Component 2 Self-Assessment points. For more information about CCP, please visit the ABD website at www.abderm.org.
LEARNING OBJECTIVES
Formulate practical management tips for itch
Utilize new drugs that target itch pathophysiology
Evaluate and manage acute and chronic itches
SCHEDULE
9:00 AM
Introduction to itch
Ethan A. Lerner, MD, PhD, FAAD
9:05 AM
Physiology of itch
Brian S Kim, MD, FAAD
9:30 AM
Measuring itch
Emily Cole, MD, MPH, FAAD
10:00 AM
Urticaria: We might understand it!
Martin Metz, MD
10:30 AM
The itchy microbiome
Tammy Gonzalez, MD, PhD
10:50 AM
Itch and aging
Daniel Charles Butler, MD, FAAD
11:10 AM
Itch and cancer therapeutics
Yevgeniy Semenov, MD, MS, FAAD
11:30 AM
Therapeutic landscape
Gil Yosipovitch, MD
11:45 AM
Q&A
DIRECTOR
Ethan A. Lerner, MD, PhD, FAAD
SPEAKERS
Daniel Charles Butler, MD, FAAD
Emily Cole, MD, MPH, FAAD
Tammy Gonzalez, MD, PhD
Brian S Kim, MD, FAAD
Martin Metz, MD
Yevgeniy Semenov, MD, MS, FAAD
Gil Yosipovitch, MD
HANDOUTS
DISCLOSURES
Daniel Charles Butler, MD, FAAD
AbbVie – Investigator(Grants/Research Funding); Dermira/Lilly – Speaker(Honoraria); Galderma – Advisory Board(Fees); Leo Pharma Inc – Advisory Board(Fees); Novartis – Advisory Board(Honoraria), Speaker(Honoraria); Pfizer Inc. – Investigator(Grants/Research Funding); Regeneron – Speaker(Honoraria);
Emily Cole, MD, MPH, FAAD
No financial relationships exist with ineligible companies.
Tammy Gonzalez, MD, PhD
No financial relationships exist with ineligible companies.
Brian S Kim, MD, FAAD
AbbVie – Consultant(Fees); Almirall – Advisory Board(Honoraria); Alys Pharmaceuticals – Stockholder Private Company(Stock); AstraZeneca – Consultant (1099 relationship)(Fees); Eli Lilly and Company – Advisory Board(Honoraria); Evommune, Inc. – Consultant (1099 relationship)(Fees); Galderma – Consultant (1099 relationship)(Fees); Guidepoint Global, LLC – Consultant(Fees); Leo Pharma Inc. – Consultant(Fees), Investigator(Grants/Research Funding); Locus Biosciences – Stockholder(Stock); Novartis – Advisory Board(Honoraria); Pfizer Inc. – Consultant(Honoraria); Recens Medical – Consultant(Fees); Regeneron – Consultant (1099 relationship)(Honoraria); Sanofi – Consultant(Fees); Septerna – Consultant (1099 relationship)(Fees);
Ethan A. Lerner, MD, PhD, FAAD
No financial relationships exist with ineligible companies.
Martin Metz, MD
AbbVie – Speaker(Honoraria); Allakos – Investigator(No Compensation Received); Allegria Therapeutics – Advisory Board(Honoraria); Almirall – Speaker(Honoraria), Speaker/Faculty Education(Honoraria); Amgen – Advisory Board(Honoraria); Arcutis Biotherapeutics – Advisory Board(Honoraria); argenx – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria); AstraZeneca – Advisory Board(Honoraria); Astria Therapeutics – Advisory Board(Honoraria); Attovia Therapeutics – Consultant (1099 relationship)(Honoraria); Bayer – Consultant (1099 relationship)(Honoraria); Berlin Chemie – Speaker(Honoraria); Blueprint Medicines – Advisory Board(Honoraria); candid – Consultant (1099 relationship)(Honoraria); Celldex – Advisory Board(Honoraria); Celltrion – Speaker(Honoraria); Deep Apple Therapeutics – Advisory Board(Honoraria); Eli Lilly – Advisory Board(Honoraria); Enanta Pharmaceuticals – Consultant (1099 relationship)(Honoraria); Escient Pharmaceuticals, Inc – Advisory Board(Honoraria); Evommune, Inc. – Advisory Board(Honoraria); Excellergy – Consultant (1099 relationship)(Honoraria); FatiAbGen – Consultant (1099 relationship)(Honoraria); Galderma – Advisory Board(Honoraria), Speaker(Honoraria); Generate Biomedicines – Consultant (1099 relationship)(Honoraria); GlaxoSmithKline Immunology – Advisory Board(Honoraria); Granular Therapeutics – Advisory Board(Honoraria); Incyte Corporation – Advisory Board(Honoraria); InflaRx – Consultant (1099 relationship)(Honoraria); Japan Tobacco Inc. – Consultant (1099 relationship)(Honoraria); Jasper Therapeutics – Advisory Board(Honoraria); Johnson & Johnson Pharmaceutical Research & Development – Advisory Board(Honoraria); Lycia Therapeutics – Consultant (1099 relationship)(Honoraria); Novartis – Advisory Board(Honoraria), Speaker(Honoraria); Ono – Consultant (1099 relationship)(Honoraria); Pfizer Inc. – Speaker(Honoraria); RAPT Therapeutics – Advisory Board(Honoraria); Regeneron Pharmaceuticals, Inc. – Advisory Board(Honoraria); Sanofi – Advisory Board(Honoraria), Speaker(Honoraria); Santa Ana Bio – Advisory Board(Honoraria); Septerna – Advisory Board(Honoraria); Tupos – Consultant (1099 relationship)(Honoraria);
Yevgeniy Semenov, MD, MS, FAAD
Alterome Therapeutics – Consultant (1099 relationship)(Honoraria); Arcutis Biotherapeutics – Consultant (1099 relationship)(Honoraria); Bristol Myers Squibb – Consultant (1099 relationship)(Honoraria); Galderma – Advisory Board(Honoraria); Journal of the American Academy of Dermatology – Other(Salary); Pfizer Inc. – Consultant (1099 relationship)(Honoraria); Pyxis Oncology – Consultant (1099 relationship)(Honoraria); Regeneron – Advisory Board(Honoraria); Sanofi – Advisory Board(Honoraria);
Gil Yosipovitch, MD
AbbVie – Advisory Board(Honoraria); Arcutis, Inc. – Advisory Board(Honoraria); Cara Therapeutics – Advisory Board(Honoraria); CeraVe – Advisory Board(Honoraria); Eli Lilly – Investigator(Fees), Investigator(Grants/Research Funding); Eli Lilly and Company – Advisory Board(Honoraria); escient – Investigator(Fees), Investigator(Grants/Research Funding); Galderma – Advisory Board(Honoraria); Galderma Laboratories, L.P. – Consultant(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); GSK – Advisory Board(Honoraria); Kamari Pharma – Consultant(Fees); Kiniksa Pharmaceuticals, Ltd. – Investigator(Grants/Research Funding); Maruho Co., Ltd – Speaker/Faculty Education(Fees); Novartis – Consultant(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); Pfizer Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Pierre Fabre – Consultant(Honoraria); Sanofi/Regeneron – Advisory Board(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); Vifor Pharma – Consultant(Fees);