U046 The Role of and Topical Therapies Involving Androgen Hormones in Acne and Androgenetic Alopecia (AGA)
DESCRIPTION
This session will address the role of androgens and hormones in the pathogenesis of acne and Androgenetic Alopecia (AGA). The latest evidence regarding hormonal and anti-androgen treatments for acne and AGA will be discussed.
LEARNING OBJECTIVES
Discuss the role of androgens and hormones in the pathogenesis of acne and Androgenetic Alopecia (AGA).
Describe the mechanism of action, effectiveness and safety of topical anti-androgens and sebum reducers in the treatment of acne.
Examine the role of anti-androgens and other therapies for Androgenetic Alopecia (AGA).
SCHEDULE
4:30 PM
The Role of Topical Therapies involving Androgen Hormones in Acne
Lawrence J Green, MD, FAAD
4:40 PM
The Role of Topical Therapies involving Androgen Hormones in Acne
Adelaide A. Hebert, MD, FAAD
5:00 PM
The role of androgens in female pattern hair loss and AGA pathogenesis
Maryanne Makredes Senna, MD, FAAD
5:10 PM
The Emerging Potential of Topical Androgen Modulators in Androgenetic Alopecia
Ken Washenik, MD, PhD, FAAD
DIRECTOR
Lawrence J Green, MD, FAAD
SPEAKERS
Adelaide A. Hebert, MD, FAAD
Maryanne Makredes Senna, MD, FAAD
Ken Washenik, MD, PhD, FAAD
HANDOUTS
DISCLOSURES
Lawrence J Green, MD, FAAD
Alphyn Biologics – Advisory Board(Honoraria); Amgen – Investigator(Honoraria), Speaker(Honoraria); Apogee BioPharm – Investigator(Grants/Research Funding); BMS – Investigator(Grants/Research Funding), Speaker(Honoraria); Dermavant Sciences, Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Eli Lilly and Company – Investigator(Grants/Research Funding); Evoimmune – Investigator(Grants/Research Funding); Galderma – Speaker(Honoraria); Galderma USA – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Incyte – Investigator(Grants/Research Funding); Incyte Corporation – Speaker(Honoraria); Ipsen – Investigator(Grants/Research Funding); Janssen Research & Development, LLC – Investigator(Grants/Research Funding); Nutrafol – Advisory Board(Honoraria); Ortho Dermatologics – Investigator(Grants/Research Funding); Oruka Therapeutics – Investigator(Grants/Research Funding); Pelthos Therapeutics – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Pfizer Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Takeda Pharmaceuticals USA Inc – Investigator(Grants/Research Funding); UCB – Consultant(Honoraria); VeraDermics Inc. – Investigator(Grants/Research Funding); Verrica Pharmaceuticals Inc – Investigator(Grants/Research Funding);
Adelaide A. Hebert, MD, FAAD
AbbVie – Advisory Board(Honoraria), Investigator(Honoraria); Almirall – Advisory Board(Honoraria); Alumis – Investigator(Grants/Research Funding); Amgen – Investigator(Grants/Research Funding), Speaker(Honoraria); Amyrt Pharma – Advisory Board(Honoraria); AnaptysBio – Investigator(Grants/Research Funding); Apogee Therapeutics – Advisory Board(Honoraria), Data Safety Monitoring Board(Honoraria); Arcutis Biotherapeutics – Investigator(Grants/Research Funding); Arcutis, Inc. – Consultant(Honoraria), Speaker(Honoraria); ASLAN Pharmaceuticals – Advisory Board(Honoraria); Beiersdorf, Inc. – Advisory Board(Honoraria); Bristol-Myers Squibb – Advisory Board(Honoraria); Castle Biosciences – Advisory Board(Honoraria); Dermavant Sciences – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Fall Clinical Dermatology Conference – Speaker(Honoraria); Galderma Laboratories, L.P. – Advisory Board(Honoraria), Speaker(Honoraria); GlaxoSmithKline – Stockholder(Stock); Healthpoint – Investigator(Grants/Research Funding); Incyte Corporation – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Innovaderm Research Inc. – Consultant(No Compensation Received); Insignia Communications – Speaker(Honoraria); Janssen Pharmaceuticals, Inc – Advisory Board(Honoraria); Kymera Therapeutics – Consultant (1099 relationship)(Honoraria); La Roche-Posay Laboratoire Pharmaceutique – Advisory Board(Honoraria); LEO Pharma, US – Advisory Board(Honoraria); Lilly ICOS LLC – Advisory Board(Honoraria); Med Learning Group – Speaker(Honoraria); Menarini Group – Speaker(Honoraria); Merz Pharmaceuticals, LLC – Stockholder(Stock); Nektar Therapeutics – Investigator(Grants/Research Funding); NIH – Investigator(Grants/Research Funding); NobelPharma – Consultant(Honoraria); Novartis Pharmaceuticals Corp. – Other(Honoraria); OCuSOFT Inc. – Consultant(Honoraria); Ortho Dermatologics – Advisory Board(Honoraria); Pediatric Dermatolology 360 – Speaker(Honoraria); Pediatric Educational Foundation – Speaker/Faculty Education(Honoraria); Pelthos Therapeutics – Speaker(Honoraria); Pfizer Inc. – Investigator(Grants/Research Funding), Other(No Compensation Received), Speaker/Faculty Education(Honoraria); PPD Inc. – Investigator(Grants/Research Funding); Regeneron – Data Safety Monitoring Board(Honoraria); Roivant Sciences – Advisory Board(Honoraria); Sanofi – Investigator(Grants/Research Funding); Sun Pharmaceutical Industries Ltd. – Speaker(Honoraria); Takeda Pharmaceuticals USA Inc – Investigator(Grants/Research Funding); UCB – Advisory Board(Honoraria), Consultant(Honoraria), Investigator(Grants/Research Funding); Ventyx Biosciences – Investigator(Grants/Research Funding); VeraDermics Inc. – Consultant(Fees); Verrica Pharmaceuticals Inc – Advisory Board(Fees); Vial – Consultant(Honoraria); VYNE Therapeutics – Advisory Board(Honoraria); Winter Clinical Dermatology Conference – Speaker(Honoraria); Xencon – Investigator(Grants/Research Funding);
Maryanne Makredes Senna, MD, FAAD
AbbVie – Advisory Board(Fees); American Hair Research Society – Board of Directors(No Compensation Received); Cicatricial Alopecia Research Foundation – Board of Directors(No Compensation Received); CoreEvitas, LLC – Advisory Board(Fees), Investigator(Grants/Research Funding); Eli Lilly and Company – Advisory Board(Fees); GLife – Advisory Board(Stock Options); Inmagene – Investigator(Grants/Research Funding); Inmagene Biopharmaceuticals – Consultant (1099 relationship)(Fees); Kintor Pharmaceutical Limited – Consultant (1099 relationship)(Fees); L'Oreal USA Inc. – Consultant (1099 relationship)(Fees); Leo Pharma Inc – Investigator(Grants/Research Funding); Pfizer Inc. – Advisory Board(Fees), Speaker(Fees); Priovant Therapeutics – Advisory Board(Fees), Investigator(Grants/Research Funding); Q32 Bio Inc. – Investigator(Grants/Research Funding); Sun Pharmaceutical Industries Ltd. – Advisory Board(Fees); Veradermics – Advisory Board(Fees), Advisory Board(Stock);
Ken Washenik, MD, PhD, FAAD
Kintor Pharmaceutical Limited – Consultant (1099 relationship)(Honoraria);