F043 Treating Tumors and Inflammatory Skin Diseases with Immunomodulators and Biologics
DESCRIPTION
The exponential growth of our understanding of immune system pathways has been equally paralleled by the development of immunomodulators that can impact the biological underpinnings of diseases instead of just symptoms. As we move towards a more personalized therapeutic approach, dermatologists must be aware of the multitude of therapies that exist, both on and off-label, and where current ongoing research is heading in order to ensure that patients are provided with all available and most appropriate treatments. Knowledge of the biological mechanisms of these treatments will improve utilization and application, as well as patient partnering and quality of care.
LEARNING OBJECTIVES
Categorize and differentiate dermatoses based on their inflammatory versus neoplastic origin and their potential responses to topical and systemic immunotherapies.
Recognize potential applications of immune-based therapies outside of conventional uses.
Select therapeutic options to modify a disease process in addition to alleviate symptoms based on the immune mechanisms that create them.
SCHEDULE
9:00 AM
Introduction/Welcome
Adam J. Friedman, MD, FAAD
9:02 AM
Biologics/Immunomodulators in Pediatric Dermatology
Colleen Cotton, MD, FAAD
9:19 AM
Immunomodulators for Chronic Spontaneous Urticaria
Adam J. Friedman, MD, FAAD
9:36 AM
Immunomodulators for Skin Cancer
Vishal Patel, MD
9:53 AM
Q&A
Adam J. Friedman, MD, FAAD, Colleen Cotton, MD, FAAD, Vishal Patel, MD
10:02 AM
Immunomodulators for Granulomatous Diseases
George Han, MD, PhD, FAAD
10:19 AM
Immunomodulators for Scarring Alopecias
Crystal Aguh, MD, FAAD
10:36 AM
Paradoxical Rashes from Biologics/Immunomodulators
Sheila Shaigany, MD, FAAD
10:51 AM
Q&A
Crystal Aguh, MD, FAAD, George Han, MD, PhD, FAAD, Sheila Shaigany, MD, FAAD
DIRECTOR
Adam J. Friedman, MD, FAAD
SPEAKERS
Crystal Aguh, MD, FAAD
Colleen Cotton, MD, FAAD
George Han, MD, PhD, FAAD
Vishal Patel, MD
Sheila Shaigany, MD, FAAD
HANDOUTS
DISCLOSURES
Crystal Aguh, MD, FAAD
CP Skin Health – Advisory Board(Honoraria); Eli Lilly and Company – Consultant(Fees); Johnson & Johnson – Other(Residency/Fellowship Program Funding); Pfizer Inc. – Consultant(Fees); Procter & Gamble Company – Consultant (1099 relationship)(Fees); UpToDate, Inc – Other(Fees); Veradermics – Advisory Board(Fees);
Colleen Cotton, MD, FAAD
Amgen – Investigator(Grants/Research Funding); CorEvitas – Investigator(Grants/Research Funding); Dermatology Foundation – Investigator(Grants/Research Funding); Galderma – Advisory Board(Honoraria); HS Foundation – Board of Directors(No Compensation Received), Investigator(Grants/Research Funding); Inner Archways LLC – Advisory Board(Other Financial Benefit); MoonLake Immunotherapeutics – Investigator(Grants/Research Funding); Novartis – Advisory Board(Honoraria); Pfizer Inc. – Consultant (1099 relationship)(No Compensation Received), Investigator(Grants/Research Funding); Pierre Fabre – Consultant(Honoraria); UCB – Investigator(Grants/Research Funding);
Adam J. Friedman, MD, FAAD
AbbVie – Advisory Board(Honoraria), Speaker/Faculty Education(Honoraria); BMS – Speaker(Honoraria); CeraVe – Other(Grants/Research Funding); Eli Lilly – Other(Grants/Research Funding), Speaker(Honoraria); Eli Lilly and Company – Advisory Board(Honoraria), Consultant(Honoraria); Galderma – Other(Grants/Research Funding), Speaker(Honoraria); Galderma USA – Consultant(Honoraria); Hoth Therapeutics – Advisory Board(Honoraria); Incyte – Data Safety Monitoring Board(Honoraria), Speaker(Honoraria); janssen – Other(Grants/Research Funding); Janssen Biotech – Speaker(Honoraria), Speaker/Faculty Education(Honoraria); Johnson and Johnson Consumer Products Company – Consultant(Honoraria); Kenvue – Advisory Board(Honoraria); La Roche-Posay Laboratorie Pharmaceutique – Advisory Board(Honoraria), Consultant(Honoraria); Medscape – Speaker/Faculty Education(Honoraria); Novartis – Advisory Board(Honoraria); Orlando Dermatology Aesthetic & Clinical (ODAC) – Speaker(Honoraria); Ortho Dermatologics – Advisory Board(Honoraria); Pfizer Inc. – Advisory Board(Honoraria), Consultant(Honoraria); Regeneron – Speaker/Faculty Education(Honoraria); Sanova Works – Consultant(Honoraria); Takeda Pharmaceuticals USA Inc – Advisory Board(Honoraria);
George Han, MD, PhD, FAAD
Aclaris Therapeutics, Inc. – Advisory Board(Honoraria); Alumis – Investigator(Grants/Research Funding); Avillion – Investigator(Grants/Research Funding); Boehringer Ingelheim – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Bristol-Myers Squibb – Advisory Board(Honoraria); Eli Lilly and Company – Advisory Board(Honoraria), Investigator(Grants/Research Funding); First Tracks Biotherapeutics – Advisory Board(Honoraria); Incyte – Investigator(Grants/Research Funding); Incyte Corporation – Advisory Board(Honoraria); Janssen Pharmaceuticals, Inc – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); LearnHealth/LearnSkin – Speaker/Faculty Education(Honoraria); Leo Pharma – Advisory Board(Honoraria); Novartis Pharmaceuticals Corp. – Investigator(Grants/Research Funding); Ortho Dermatologics – Advisory Board(Honoraria); Pfizer Inc. – Speaker(Honoraria); Regeneron Pharmaceuticals, Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Sanofi – Advisory Board(Honoraria); Sanofi Genzyme – Speaker(Honoraria); Sun Pharmaceutical Industries Ltd. – Speaker(Honoraria); Takeda Pharmaceuticals USA Inc – Advisory Board(Honoraria); UCB – Advisory Board(Honoraria), Speaker(Honoraria);
Vishal Patel, MD
Almirall – Speaker(Honoraria); Gerson Lehrman Group – Consultant(Fees); Regeneron – Speaker(Honoraria); Regeneron Pharmaceuticals, Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Sun Pharmaceutical Industries Ltd. – Advisory Board(Honoraria), Speaker(Honoraria);
Sheila Shaigany, MD, FAAD
Blueprint Medicines – Advisory Board(Honoraria); Boehringer Ingelheim – Advisory Board(Honoraria), Investigator(No Compensation Received); Hoth Therapeutics – Investigator(No Compensation Received); Priovant Therapeutics – Consultant (1099 relationship)(Honoraria), Investigator(No Compensation Received);