F041 Atopic Dermatitis
DESCRIPTION
The treatment landscape in pediatric and adult atopic dermatitis (AD) is changing rapidly. With the advent of new topical and systemic therapies, how do we know which treatment is right for our patients? How should I incorporate new and emerging topicals into the treatment regimen? How do I identify a patient who needs systemic therapy? What is considered the best first-line systemic? What is considered an inadequate response? When should we switch biologics? Should I switch to an oral JAK inhibitor after 1 biologic failure? Can I start an oral JAK inhibitor as first-line systemic therapy? Come hear expert clinician scientists provide data and opinion to the toughest questions in AD.
LEARNING OBJECTIVES
Describe the mechanisms of action, efficacy and side effects for new topical and systemic therapies in AD.
Develop an individualized topical treatment plan utilizing current and anticipated new topical therapies.
Formulate a plan if biologics provide an inadequate response.
SCHEDULE
9:00 AM
Hot Topics and Controversies in Atopic Dermatitis
Eric Lawrence Simpson, MD, FAAD
9:20 AM
Q&A
9:30 AM
Biologics- Initiating, Assessing, Switching, Stopping
Melinda Gooderham, MD, FAAD
9:50 AM
Q&A
10:00 AM
Oral JAK Inhibitors- When and How?
Raj J Chovatiya, MD, PhD, FAAD
10:20 AM
Q&A
10:30 AM
Incorporating New Non-steroidal Topicals into Practice
Lawrence F Eichenfield, MD, FAAD
10:50 AM
Q&A
DIRECTOR
Eric Lawrence Simpson, MD, FAAD
SPEAKERS
Raj J Chovatiya, MD, PhD, FAAD
Lawrence F Eichenfield, MD, FAAD
Melinda Gooderham, MD, FAAD
DISCLOSURES
Raj J Chovatiya, MD, PhD, FAAD
AbbVie – Consultant(Fees), Speaker(Honoraria); Acelyrin – Consultant (1099 relationship)(Fees); Alumis – Consultant (1099 relationship)(Fees); Amgen – Consultant (1099 relationship)(Fees); Apogee Therapeutics – Consultant(Fees); Arcutis Biotherapeutics – Consultant(Fees), Speaker(Fees); arGEN-X – Consultant(Fees); ASLAN Pharmaceuticals – Consultant(Fees); Astria Therapeutics – Consultant (1099 relationship)(Fees); Avalere Health – Consultant (1099 relationship)(Honoraria); Beiersdorf, Inc. – Consultant(Fees), Speaker(Fees); Boehringer Ingelheim – Consultant(Fees), Speaker(Honoraria); Bristol-Myers Squibb – Consultant(Fees), Speaker(Honoraria); Cara Therapeutics – Consultant(Fees); Castle Biosciences – Consultant (1099 relationship)(Fees); Dermavant Sciences – Consultant(Fees), Speaker(Fees); Eli Lilly and Company – Consultant(Fees), Investigator(Grants/Research Funding), Speaker(Fees); EMD Serono – Consultant (1099 relationship)(Fees); Formation Bio – Consultant (1099 relationship)(Fees); Foundation for Research & Education of Dermatology – Speaker/Faculty Education(Honoraria); Galderma – Consultant (1099 relationship)(Fees), Speaker(Fees); Genentech, Inc. – Consultant(Fees); GlaxoSmithKline Immunology – Consultant (1099 relationship)(Fees); Incyte Corporation – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); Johnson & Johnson Innovative Medicine – Consultant (1099 relationship)(Fees); Kenvue – Consultant (1099 relationship)(Fees); L'Oreal USA Inc. – Consultant (1099 relationship)(Fees); Leo Pharma Inc. – Consultant(Fees), Speaker(Fees); Maui Derm – Speaker/Faculty Education(Honoraria); National Eczema Association – Speaker/Faculty Education(Honoraria); Nektar Therapeutics – Consultant (1099 relationship)(Fees); Novartis – Speaker(Fees); Opsidio – Consultant (1099 relationship)(Fees); Pfizer Inc. – Consultant(Fees), Speaker(Fees); RAPT Therapeutics – Consultant (1099 relationship)(Fees); Regeneron – Consultant(Fees), Speaker(Fees); Sanofi – Consultant(Fees), Speaker(Fees); Sitryx – Consultant (1099 relationship)(Fees); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Fees); TRex Bio – Consultant (1099 relationship)(Fees); UCB – Consultant(Fees), Speaker(Honoraria);
Lawrence F Eichenfield, MD, FAAD
Abbvie – Investigator(Grants/Research Funding); Abeona Therapeutics – Consultant (1099 relationship)(Honoraria); Acrotech Biopharma Inc – Consultant (1099 relationship)(Honoraria); Almirall – Consultant(Honoraria); Amgen – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Apogee Therapeutics – Consultant (1099 relationship)(Honoraria); Arcutis Biotherapeutics – Investigator(Grants/Research Funding); Arcutis, Inc. – Consultant (1099 relationship)(Honoraria); Attovia Therapeutics – Consultant (1099 relationship)(Fees); Bristol-Myers Squibb – Consultant(Honoraria); Castle Biosciences – Consultant (1099 relationship)(Honoraria); Castle Biosciences, Inc – Investigator(Grants/Research Funding); Chiesi Farmaceutici – Consultant (1099 relationship)(Honoraria); Dermata Therapeutics – Consultant (1099 relationship)(Stock); Dermavant Sciences, Inc. – Consultant(Honoraria); Eli Lilly – Consultant(Honoraria), Investigator(Grants/Research Funding); Elsevier Inc. – Other(Patent royalties or other compensation for Intellectual Property Rights); Forte Biosciences – Consultant (1099 relationship)(Honoraria); Galderma Laboratories, L.P. – Consultant(Honoraria), Investigator(Fees); Incyte Corporation – Consultant(Honoraria); Janssen Pharmaceuticals, Inc – Consultant (1099 relationship)(Honoraria); Kenvue – Consultant (1099 relationship)(Honoraria); Krystal Biotech, Inc – Consultant(Honoraria); Kymera Therapeutics – Consultant (1099 relationship)(Honoraria); LEO Pharma, US – Consultant(Honoraria), Investigator(Fees); Lilly ICOS LLC – Consultant(Honoraria); Novartis – Consultant (1099 relationship)(Honoraria); Organon – Consultant (1099 relationship)(Honoraria); Ortho Dermatologics – Consultant (1099 relationship)(Honoraria); Pfizer Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); Sanofi/Regeneron – Consultant(Honoraria), Investigator(Fees); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Honoraria); Target RWE – Investigator(Grants/Research Funding); TopMD – Consultant(Stock Options); TRex Bio – Consultant (1099 relationship)(Honoraria); TrialSpark, Inc. – Consultant(Honoraria); UCB – Consultant(Honoraria); Verrica Pharmaceuticals Inc – Board of Directors(Fees), Board of Directors(Stock Options); Wiley-Blackwell – Other(Honoraria);
Melinda Gooderham, MD, FAAD
AbbVie – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Acelyrin – Investigator(Grants/Research Funding); Amgen – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); AnaptysBio – Investigator(Grants/Research Funding); Arcutis Biotherapeutics – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Aristea Therapeutics – Investigator(Grants/Research Funding); ASLAN Pharmaceuticals – Investigator(Grants/Research Funding); Bausch Health – Consultant(Honoraria), Investigator(Grants/Research Funding); Boehringer Ingelheim – Advisory Board(Honoraria), Consultant(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Bristol-Myers Squibb – Consultant(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Cara Therapeutics – Investigator(Grants/Research Funding); Dermavant Sciences – Investigator(Grants/Research Funding); Eli Lilly and Company – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker/Faculty Education(Honoraria); Galderma Laboratories, LP – Investigator(Grants/Research Funding), Speaker(Honoraria); Incyte – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Inmagene Biopharmaceuticals – Investigator(Grants/Research Funding); Janssen Pharmaceuticals, Inc – Advisory Board(Honoraria), Consultant(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Leo Pharma Inc – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Leo Pharma Inc. – Speaker(Honoraria); Meiji Seika Pharma Co., Ltd – Investigator(Grants/Research Funding); Moonlake – Investigator(Grants/Research Funding); Nimbus Therapeutics – Investigator(Grants/Research Funding); Novartis Pharmaceuticals Corp. – Consultant(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Pfizer Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Regeneron – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Reistone Biopharma – Investigator(Grants/Research Funding); Sanofi Genzyme – Consultant(Honoraria), Speaker(Honoraria); Sanofi/Regeneron – Advisory Board(Honoraria); Sun Pharmaceutical Industries Ltd. – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Takeda Pharmaceuticals USA Inc – Advisory Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Tarsus – Investigator(Grants/Research Funding); UCB – Advisory Board(Honoraria), Data Safety Monitoring Board(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria); Ventyx Biosciences – Investigator(Grants/Research Funding); VYNE Therapeutics – Investigator(Grants/Research Funding);
Eric Lawrence Simpson, MD, FAAD
AbbVie – Consultant(Fees), Investigator(Grants/Research Funding); Aclaris Therapeutics Inc. – Consultant (1099 relationship)(Fees); Acrotech Biopharma Inc – Investigator(Grants/Research Funding); Almirall – Consultant (1099 relationship)(Fees); Amgen – Consultant(Fees), Investigator(Grants/Research Funding); Arcutis Biotherapeutics – Consultant(Fees); Arcutis, Inc. – Investigator(Grants/Research Funding); ASLAN – Investigator(Grants/Research Funding); Astria Therapeutics – Consultant (1099 relationship)(Fees); Attovia Therapeutics, Inc – Consultant (1099 relationship)(Fees); Bambusa Therapeutics Inc – Consultant (1099 relationship)(Fees); Castle Biosciences – Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); CorEvitas – Consultant(Fees), Investigator(Grants/Research Funding); Demira – Consultant(Fees); Dermavant – Investigator(Grants/Research Funding); Dermira – Investigator(Grants/Research Funding); Eli Lilly and Company – Consultant(Fees), Investigator(Grants/Research Funding); Evomunne – Consultant (1099 relationship)(Fees); FIDE – Speaker/Faculty Education(Fees); Genentech, Inc. – Consultant (1099 relationship)(Fees); Impetus Healthcare – Consultant (1099 relationship)(Fees); Incyte Corporation – Consultant(Fees), Investigator(Grants/Research Funding); Infinimmune – Advisory Board(Fees); Inmagene Biopharmaceuticals – Consultant (1099 relationship)(Fees); Innovaderm Research Inc. – Consultant (1099 relationship)(Fees); Janssen Pharmaceuticals, Inc – Consultant (1099 relationship)(Fees); Kha Khanda UK Employco LTD – Consultant (1099 relationship)(Fees); Kymera Therapeutics – Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); La Fonderie Ressources – Consultant (1099 relationship)(Fees); Leo Pharma Inc. – Consultant(Fees); National Jewish Health – Investigator(Grants/Research Funding); Nektar Therapeutics – Consultant (1099 relationship)(Fees); NUMAB Therapeutics AG – Consultant (1099 relationship)(Fees); Pfizer Inc. – Consultant(Fees), Investigator(Grants/Research Funding); Recludix Pharma – Consultant (1099 relationship)(Fees); Regeneron – Consultant(Fees), Investigator(Grants/Research Funding); Roche Products Ltd – Consultant (1099 relationship)(Fees); Sanofi – Investigator(Grants/Research Funding); Sanofi Genzyme – Consultant(Fees), Investigator(Grants/Research Funding); SITRYX – Consultant (1099 relationship)(Fees); Target RWE – Investigator(Grants/Research Funding); UCB – Consultant (1099 relationship)(Fees); Veriskin – Investigator(Grants/Research Funding);