S018 Psoriasis
DESCRIPTION
Join this exciting psoriasis symposium, where the learners will gain high-yield, practical information on the management of psoriasis using topical, oral, and biologic therapies. We will describe and differentiate the mechanisms of action, efficacy, and safety among FDA-approved and emerging therapies to treat psoriasis. We will also discuss the management of difficult-to-treat subtypes of psoriasis such as nail psoriasis. Additionally, learners will hear updates on biomarker development in psoriasis and management of psoriatic arthritis. Finally, the symposium will have two spirited debates: (1) whether non-steroidal topical medications replace topical steroids in the treatment of psoriasis, and (2) oral versus biologic therapy for the treatment of mild to moderate psoriasis. Come to be informed, inspired, and entertained.
LEARNING OBJECTIVES
Differentiate the mechanisms of action of psoriasis therapies and describe novel insights in biomarkers for psoriasis and psoriatic arthritis and their clinical applications.
Discuss the practical use of topical, oral, and biologic therapies for the management of psoriasis and psoriatic arthritis.
Debate (1) whether non-steroidal topical medications will replace topical steroids in the treatment of psoriasis (2) oral versus biologic therapy for the treatment of mild-to-moderate psoriasis.
SCHEDULE
1:00 PM
Welcome and Introduction
April W. Armstrong, MD, MPH, FAAD
1:05 PM
Novel Insights in Biomarkers for Psoriasis and Psoriatic Arthritis and Their Clinical Applications
Andrew Blauvelt, MD, FAAD
1:20 PM
Evolving Landscape of Oral Therapies for Psoriasis
April W. Armstrong, MD, MPH, FAAD
1:35 PM
Nail psoriasis or onychomycosis? Pearls on diagnosis and management of psoriatic nail disease
Boni E. Elewski, MD, FAAD
1:50 PM
Debate #1: Will non-steroidal topical medications replace topical steroids in the treatment of psoriasis?
Kenneth B. Gordon, MD, FAAD, Bruce Elliot Strober, MD, PhD, FAAD
2:25 PM
Mastering the Use of IL-23 inhibitors in psoriasis and psoriatic arthritis
Joel M. Gelfand, MD, MSCE, FAAD
2:40 PM
Practical considerations in Using IL-17 inhibitors for psoriasis and psoriatic arthritis
Joseph Merola, MD, MSc, FAAD
2:55 PM
Doppelgängers or Twins? What to know about biosimilars
Mark Lebwohl, MD, FAAD
3:10 PM
Debate #2: Oral versus biologic therapy for the treatment of mild to moderate psoriasis
Kristina Patrice Callis-Duffin, MD, FAAD, Wilson Liao, MD, FAAD
3:45 PM
Question and Answer
DIRECTOR
April W. Armstrong, MD, MPH, FAAD
SPEAKERS
Andrew Blauvelt, MD, FAAD
Kristina Patrice Callis-Duffin, MD, FAAD
Boni E. Elewski, MD, FAAD
Joel M. Gelfand, MD, MSCE, FAAD
Kenneth B. Gordon, MD, FAAD
Mark Lebwohl, MD, FAAD
Wilson Liao, MD, FAAD
Joseph Merola, MD, MSc, FAAD
Bruce Elliot Strober, MD, PhD, FAAD
HANDOUTS
DISCLOSURES
April W. Armstrong, MD, MPH, FAAD
AbbVie – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Amgen – Advisory Board(Honoraria); Arcutis Biotherapeutics – Consultant(Honoraria); Boehringer Ingelheim – Data Safety Monitoring Board(Honoraria); Bristol-Myers Squibb – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Dermavant Sciences, Inc. – Consultant(Honoraria); Dermsquared – Advisory Board(Honoraria); Eli Lilly and Company – Advisory Board(Honoraria); Galderma USA – Advisory Board(Honoraria); Incyte – Consultant (1099 relationship)(Honoraria); Janssen Biotech – Consultant (1099 relationship)(Honoraria); Leo Pharma Inc – Consultant(Honoraria); Novartis – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Ortho Dermatologics – Speaker(Honoraria); Pfizer Inc. – Advisory Board(Honoraria); Regeneron – Advisory Board(Honoraria); Sanofi Genzyme – Consultant(Honoraria); Sun Pharmaceutical Industries Ltd. – Advisory Board(Honoraria); Takeda Pharmaceuticals USA Inc – Advisory Board(Honoraria), Investigator(Grants/Research Funding); UCB – Advisory Board(Honoraria);
Andrew Blauvelt, MD, FAAD
AbbVie – Consultant(Honoraria); Almirall – Consultant(Honoraria); Alumis – Consultant (1099 relationship)(Honoraria); Amgen – Consultant (1099 relationship)(Honoraria); AnaptysBio – Consultant (1099 relationship)(Honoraria); Apogee Therapeutics – Consultant (1099 relationship)(Honoraria); Arcutis, Inc. – Consultant (1099 relationship)(Honoraria); Eli Lilly and Company – Consultant(Honoraria), Speaker(Honoraria); Incyte Corporation – Consultant(Honoraria); Janssen-Ortho Inc. – Consultant(Honoraria); Leo Pharma Inc – Consultant(Honoraria); Novartis Pharmaceuticals Corp. – Consultant(Honoraria); Oruka Therapeutics – Consultant (1099 relationship)(Honoraria), Stockholder Public Company(Stock); Pfizer Inc. – Consultant(Honoraria); Regeneron – Consultant(Honoraria); Sanofi – Consultant(Honoraria); Sun Pharmaceutical Industries Ltd. – Consultant(Honoraria); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Honoraria); UCB – Consultant(Honoraria), Speaker(Honoraria);
Kristina Patrice Callis-Duffin, MD, FAAD
AbbVie – Consultant(Honoraria), Investigator(Grants/Research Funding), Speaker(Honoraria), Stockholder Public Company(No Compensation Received); Alumis – Investigator(Grants/Research Funding); Amgen – Advisory Board(Honoraria), Consultant(Honoraria); Boehringer Ingelheim – Advisory Board(Honoraria), Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol-Myers Squibb – Advisory Board(Honoraria), Consultant(Fees); Celgene Corporation – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Eli Lilly and Company – Consultant(Honoraria), Investigator(Grants/Research Funding); FIDE – Consultant (1099 relationship)(Honoraria); Janssen Pharmaceuticals, Inc – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Novartis – Consultant(Honoraria), Investigator(Grants/Research Funding); Oruka Therapeutics – Consultant (1099 relationship)(Honoraria); Pfizer Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); UCB – Stockholder Public Company(No Compensation Received);
Boni E. Elewski, MD, FAAD
AbbVie – Investigator(Grants/Research Funding); Amgen – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Boehringer Ingelheim – Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol-Myers Squibb – Investigator(Grants/Research Funding); Eli Lilly and Company – Investigator(Grants/Research Funding); Foundation for Research & Education of Dermatology – Advisory Board(Honoraria); Incyte Corporation – Investigator(Grants/Research Funding); Janssen Pharmaceuticals, Inc – Consultant (1099 relationship)(Honoraria); Janssen-Ortho Inc. – Investigator(Grants/Research Funding); Novartis Pharmaceuticals Corp. – Consultant(Honoraria), Investigator(Grants/Research Funding); Pfizer Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); UCB – Consultant(Honoraria), Investigator(Grants/Research Funding);
Joel M. Gelfand, MD, MSCE, FAAD
AbbVie – Consultant(Fees); Alumis – Consultant (1099 relationship)(Fees); Alyson Oliver Partner & Attorney – Consultant (1099 relationship)(Fees); Arcutis Biotherapeutics – Consultant (1099 relationship)(Fees); Arnold & Porter – Consultant (1099 relationship)(Fees); Boehringer Ingelheim – Consultant (1099 relationship)(Fees); Bristol Myers Squibb – Investigator(Grants/Research Funding); Eli Lilly and Company – Investigator(Grants/Research Funding); FIDE – Consultant(Fees); Healio – Other(Fees); Inmagene Biopharmaceuticals – Data Safety Monitoring Board(Fees); International Psoriasis Council – Board of Directors(No Compensation Received); Johnson & Johnson Innovative Medicine – Consultant (1099 relationship)(Fees); Leo Pharma Inc – Consultant(Fees); Maui Derm – Speaker/Faculty Education(Fees); Medical Dermatology Society – Board of Directors(No Compensation Received); Moonlake – Data Safety Monitoring Board(Fees); National Psoriasis Foundation – Investigator(Grants/Research Funding); Neuroderm LTD – Other(Fees); Oruka Therapeutics – Consultant (1099 relationship)(Fees); Pfizer Inc. – Consultant (1099 relationship)(Fees);
Kenneth B. Gordon, MD, FAAD
AbbVie – Consultant(Honoraria), Investigator(Grants/Research Funding); Almirall – Consultant(Honoraria); Amgen – Consultant(Honoraria); Arcutis, Inc. – Consultant(Honoraria); Boehringer Ingelheim – Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol-Myers Squibb – Consultant(Honoraria); Dermavant Sciences – Consultant(Honoraria); Eli Lilly and Company – Investigator(Grants/Research Funding); Incyte Corporation – Consultant(Honoraria); Janssen Pharmaceuticals, Inc – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Leo Pharma Inc – Consultant(Honoraria); Lilly ICOS LLC – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria); Novartis Pharmaceuticals Corp. – Advisory Board(Honoraria); Othro Dermatologics – Consultant(Honoraria); Pfizer Inc. – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria); Protagonist Therapeutics – Consultant (1099 relationship)(Honoraria); Sanofi Genzyme – Consultant(Honoraria); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); UCB – Consultant(Honoraria);
Mark Lebwohl, MD, FAAD
AbbVie – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Added Health – Consultant (1099 relationship)(Honoraria); Aikium – Consultant (1099 relationship)(Honoraria); Almirall – Consultant(Honoraria); AltruBio Inc. – Consultant(Honoraria); Alumis – Consultant (1099 relationship)(Honoraria); Amgen – Consultant (1099 relationship)(Honoraria); Apogee Therapeutics – Consultant(Honoraria); Arcutis, Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); AstraZeneca – Consultant (1099 relationship)(Honoraria); Atomwise – Consultant(Honoraria); Avotres, Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); Bausch Health – Consultant (1099 relationship)(Honoraria); Boehringer Ingelheim – Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol Myers Squibb – Investigator(Grants/Research Funding); Bristol-Myers Squibb – Consultant(Honoraria); Cara Therapeutics – Investigator(Grants/Research Funding); Castle Biosciences, Inc – Consultant(Honoraria); Celltrion – Consultant(Honoraria); Clexio Biosciences, Ltd – Investigator(Grants/Research Funding); CoreEvitas, LLC – Consultant(Honoraria); Dermavant Sciences – Consultant(Honoraria), Investigator(Grants/Research Funding); Dermsquared – Consultant (1099 relationship)(Honoraria); Edesa Biotech – Consultant (1099 relationship)(Honoraria); Eli Lilly – Consultant (1099 relationship)(Honoraria); Eli Lilly and Company – Investigator(Grants/Research Funding); Evommune, Inc. – Consultant(Honoraria); Facilitation of International Dermatology Education – Consultant(Honoraria); Forte Biosciences – Consultant(Honoraria); Galderma – Consultant(Honoraria); Genentech, Inc. – Consultant(Honoraria); Incyte Corporation – Consultant(Honoraria), Investigator(Grants/Research Funding); Inozyme Pharma – Investigator(Grants/Research Funding); J&J Innovative Medicine – Consultant (1099 relationship)(Honoraria); Janssen Research & Development, LLC – Investigator(Grants/Research Funding); Leo Pharma A/S – Consultant(Honoraria); Mayne Pharma Group – Consultant (1099 relationship)(Honoraria); Meiji Seika Pharma Co., Ltd – Consultant(Honoraria); Mindera – Consultant(Honoraria); Mirum Pharmaceuticals, Inc. – Consultant (1099 relationship)(Honoraria); MoonLake Immunotherapeutics – Consultant (1099 relationship)(Honoraria); New York College of Podiatric Medicine – Speaker/Faculty Education(Honoraria); Oruka Therapeutics – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Pfizer Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); Revolo Therapeutics – Consultant (1099 relationship)(Honoraria); Sanofi/Regeneron – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Seanergy Maritime Holdings Corp. – Consultant(Honoraria); Strata Skin Sciences – Consultant(Honoraria); Sun Pharmaceutical Industries Ltd. – Consultant (1099 relationship)(Honoraria); Takeda Pharmaceuticals USA Inc – Consultant (1099 relationship)(Honoraria); Teva Pharmaceutical Industries Ltd. – Consultant (1099 relationship)(Honoraria); Trevi Therapeutics – Consultant(Honoraria); UCB – Investigator(Grants/Research Funding); Verrica Pharmaceuticals Inc – Consultant(Honoraria);
Wilson Liao, MD, FAAD
Amgen – Investigator(Grants/Research Funding); Gilead Sciences, Inc – Investigator(Grants/Research Funding); Janssen Pharmaceuticals, Inc – Investigator(Grants/Research Funding); Leo Pharma Inc – Investigator(Grants/Research Funding); Regeneron – Investigator(Grants/Research Funding); Takeda Pharmaceuticals USA Inc – Investigator(Grants/Research Funding);
Joseph Merola, MD, MSc, FAAD
Consultant(Honoraria); Amgen – Advisory Board(Honoraria); AstraZeneca – Consultant (1099 relationship)(Fees); Biogen – Consultant (1099 relationship)(Fees); Boehringer Ingelheim – Consultant (1099 relationship)(Fees); Bristol-Myers Squibb – Consultant (1099 relationship)(Fees); Eli Lilly and Company – Consultant(Honoraria); Galderma – Consultant (1099 relationship)(Fees); Janssen Pharmaceuticals, Inc – Consultant(Honoraria); MoonLake Immunotherapeutics – Consultant (1099 relationship)(Fees); Novartis – Consultant(Honoraria); Pfizer Inc. – Investigator(Fees); Sanofi/Regeneron – Consultant(Honoraria); Sun Pharmaceutical Industries Ltd. – Consultant (1099 relationship)(Fees); UCB – Consultant(Honoraria);
Bruce Elliot Strober, MD, PhD, FAAD
AbbVie – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); Alumis – Consultant(Fees); Amgen – Consultant (1099 relationship)(Fees); Arcutis, Inc. – Consultant(Fees), Speaker(Honoraria); Boehringer Ingelheim – Consultant(Honoraria); Bristol Myers Squibb – Speaker(Honoraria); Bristol-Myers Squibb – Advisory Board(Honoraria), Consultant(Fees); Connect Biopharma LLC – Stockholder(Other Financial Benefit); CoreEvitas, LLC – Advisory Board(Honoraria), Investigator(Fees); Eli Lilly and Company – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); Johnson and Johnson – Advisory Board(Honoraria), Consultant (1099 relationship)(Fees), Speaker(Honoraria); Leo Pharma Inc – Advisory Board(Honoraria), Consultant(Honoraria); Meiji Seika Pharma Co., Ltd – Consultant(Fees); Mindera – Stockholder(Other Financial Benefit); Novartis Pharmaceuticals Corp. – Advisory Board(Honoraria), Consultant(Honoraria); Oruka Therapeutics – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Pfizer Inc. – Consultant(Honoraria); Sanofi/Regeneron – Advisory Board(Honoraria), Consultant(Honoraria), Speaker(Honoraria); UCB – Advisory Board(Honoraria), Consultant(Fees), Speaker(Honoraria);