S003 Chronic Pruritus: Bedside to Bench Perspectives
DESCRIPTION
Itch is both a disease and a symptom of disease. Chronic pruritus impacts patient quality of life. Successful treatment is finally available as a result of advances in understanding of itch physiology and pathophysiology accompanied by targeted therapeutic approaches. This session is geared toward the practicing physician. It addresses advances in understanding and measuring itch, workup of the itchy patient and cutting edge approaches to treatment. This activity has been approved by the American Board of Dermatology (ABD) for up to 30 Continuous Certification Program (CCP) Component 2 Self-Assessment points. For more information about CCP, please visit the ABD website at www.abderm.org.
LEARNING OBJECTIVES
Describe the pathophysiology of itch
Recognize how itch is measured in clinical trials
Evaluate and manage acute and chronic itches
SCHEDULE
9:00 AM
Introduction
Ethan A. Lerner, MD, PhD, FAAD
9:05 AM
Physiology of itch
Brian S Kim, MD, FAAD
9:30 AM
Measuring itch
Emily Cole, MPH, MD, FAAD
10:00 AM
Wearable sensors for scratching an itch
Steve Xu, MD, FAAD
10:30 AM
Vulvar itch
Ginat W. Mirowski, MD, DMD, FAAD
11:00 AM
The itch of cancer therapeutics
Mario E Lacouture, MD, FAAD
11:30 AM
The new era of treating itch
Gil Yosipovitch, MD
11:45 AM
Q&A
DIRECTOR
Ethan A. Lerner, MD, PhD, FAAD
SPEAKERS
Emily Cole, MPH, MD, FAAD
Brian S Kim, MD, FAAD
Mario E Lacouture, MD, FAAD
Ginat W. Mirowski, MD, DMD, FAAD
Steve Xu, MD, FAAD
Gil Yosipovitch, MD
HANDOUTS
DISCLOSURES
Emily Cole, MPH, MD, FAAD
No financial relationships exist with ineligible companies.
Brian S Kim, MD, FAAD
AbbVie – Consultant(Fees); Almirall – Advisory Board(Honoraria); Alys Pharmaceuticals – Stockholder Private Company(Stock); AstraZeneca – Consultant (1099 relationship)(Fees); Eli Lilly and Company – Advisory Board(Honoraria); Evommune, Inc. – Consultant (1099 relationship)(Fees); Galderma – Consultant (1099 relationship)(Fees); Guidepoint Global, LLC – Consultant(Fees); Leo Pharma Inc. – Consultant(Fees), Investigator(Grants/Research Funding); Locus Biosciences – Stockholder(Stock); Novartis – Advisory Board(Honoraria); Pfizer Inc. – Consultant(Honoraria); Recens Medical – Consultant(Fees); Regeneron – Consultant (1099 relationship)(Honoraria); Sanofi – Consultant(Fees); Septerna – Consultant (1099 relationship)(Fees);
Mario E Lacouture, MD, FAAD
AstraZeneca – Investigator(Grants/Research Funding); Janssen Pharmaceuticals, Inc – Consultant(Fees); Johnson and Johnson – Consultant(Honoraria), Investigator(Grants/Research Funding); Kintara Therapeutics, Inc. – Advisory Board(Honoraria); La Roche Posay Dermatologique – Advisory Board(Fees); Novartis – Consultant(Honoraria); Novocure – Consultant(Honoraria), Investigator(Grants/Research Funding); OncoDerm LLC – Advisory Board(No Compensation Received); OnQuality Pharmaceuticals, Ltd. – Consultant(Fees), Other(Grants/Research Funding); Paxman – Investigator(Grants/Research Funding); Seattle Genetics – Consultant(Fees); Tyra Biosciences – Consultant(Fees); Wiley & Sons, Inc. – Other(Fees);
Ethan A. Lerner, MD, PhD, FAAD
No financial relationships exist with ineligible companies.
Ginat W. Mirowski, MD, DMD, FAAD
UpToDate, Inc. – Other(Honoraria);
Steve Xu, MD, FAAD
Maruho Co., Ltd – Investigator(Grants/Research Funding); Sibel Health Inc. – Founder(Stock);
Gil Yosipovitch, MD
AbbVie – Advisory Board(Honoraria); Arcutis, Inc. – Advisory Board(Honoraria); Cara Therapeutics – Advisory Board(Honoraria); CeraVe – Advisory Board(Honoraria); Eli Lilly – Investigator(Fees), Investigator(Grants/Research Funding); Eli Lilly and Company – Advisory Board(Honoraria); escient – Investigator(Fees), Investigator(Grants/Research Funding); Galderma – Advisory Board(Honoraria); Galderma Laboratories, L.P. – Consultant(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); GSK – Advisory Board(Honoraria); Kamari Pharma – Consultant(Fees); Kiniksa Pharmaceuticals, Ltd. – Investigator(Grants/Research Funding); Maruho Co., Ltd – Speaker/Faculty Education(Fees); Novartis – Consultant(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); Pfizer Inc. – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Pierre Fabre – Consultant(Honoraria); Sanofi/Regeneron – Advisory Board(Honoraria), Investigator(Fees), Investigator(Grants/Research Funding); Vifor Pharma – Consultant(Fees);